MDPHP is a cathinone and more specifically a pyrovalerone. This means the molecule has a core amphetamine structure with a β-keto substitution (making it a cathinone) and it has a pyrrolidine ring substitution at its nitrogen atom (making it a pyrovalerone). From there, MDPHP includes a 3′,4′-methylenedioxy group, similar to MDPV. That group is the only difference between MDPHP and α-PHP. No formal pharmacological studies have been conducted, so the drug’s mode of action can only be theorized based on its subjective effects and its similarity to other cathinones/pyrovalerones that have been studied. It probably functions at least as a reuptake inhibitor for dopamine and norepinephrine, and some reports claim a serotonergic component could also be present. Direct binding at receptors, intracellular activity, and other potential effects have not been evaluated. Very little is known about MDPHP in terms of toxicity, pharmacology and metabolism.