Clomiphene Citrate

in stock

Clomifene is in the selective estrogen receptor modulator (SERM) family of medication and works by causing the release of GnRH by the hypothalamus, and subsequently gonadotropin from the anterior pituitary. Usually it's a medication used to treat infertility in women who do not ovulate and for polycystic ovary syndrome.

Synonyms:clomiphen, Clomifenum, Clomifeno, Cisclomiphene
CAS:911-45-5
Formula:C26H28ClNO
Molecular weight:405.966 g/mol
Compound purity:≥98%
IUPAC:2-hydroxypropane-1,2,3-tricarboxylic acid; {2-[4-(2-chloro-1,2-diphenylethenyl)phenoxy]ethyl}diethylamine
Clomiphene has both estrogenic and anti-estrogenic activities that compete with estrogen for binding at estrogen receptor sites in target tissues. This agent causes the release of the pituitary gonadotropins follicle stimulating hormone (FSH) and luteinizing hormone (LH), leading to ovulation. It was synthesized in 1956; after its biological activity was confirmed a patent was filed and issued in November 1959. Clinical studies were conducted under an Investigational New Drug Application. It was first used to treat cases of oligomenorrhea but was expanded to include treatment of anovulation when women undergoing treatment had higher than expected rates of pregnancy. Clomifene is included on the World Anti-Doping Agency list of illegal doping agents in sport.
 
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