Metribolone

in stock

Metribolone (R1881, methyltrienolone) is a synthetic and orally active anabolic-androgenic steroid. It's was never marketed for medical use but has been used in scientific research as a hot ligand.

Synonyms:Methyltrienolone, 17?-Methyltrenbolone; R1881
CAS:965-93-5
Formula:C19H24O2
Molecular weight:284.393 g/mol
Compound purity:≥98%
IUPAC:(8S,13S,14S,17S)-17-Hydroxy-13,17-dimethyl-1,2,6,7,8,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
It was investigated for the treatment of advanced breast cancer in women but was found to produce signs of severe hepatotoxicity, it's development was subsequently discontinued. Application can be found in: chlormadinone acetate exhibiting antiandrogenic activity in androgen-dependent cell line in endocrinology, a metal chelator suppressing cell growth and disrupting androgen receptor signaling in prostate carcinoma cell lines; effect of organochlorine pesticides on human androgen receptor activation.
 
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